Certain pharmaceutical or biotechnological products must be stored, transported or handled in precise temperature conditions or within specific temperature brackets.

Some of such thermo-sensitive products can be rendered totally redundant in the event of exposure to too high temperatures during storage. Other products can also be affected by exposure to negative temperatures even for short periods of time.

The World Health Organisation (WHO) was at the origin of the Time Temperature Integration concept at the start of the eighties and has made the use of this device compulsory for the last ten years in the context of vaccination programmes (BCG, yellow fever, Hepatitis B…) in developing countries. In this context, the tool enables the WHO to reduce waste significantly and to prevent the use of vaccinations that have been damaged by heat.